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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0a5f82117a15203c2bdd2c04bb636ee7732267f5cc4c02ddcc83742915d446' 
  AND token = 'GN4Y8lW+EB4jP9tbjOMTNTIoYXByf/kxydY4/UUaYTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}