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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e41288b773326ca7a8bbed057fcae189d284cdde0366db450f16eba61d3b09d' 
  AND token = 'ohPxxX3xkdqzIk7SRCvbOpjH0hrbXRIcCyXwMs7XaKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}