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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d55360e4943df2f092b82c90a6b16ce8a7c2d407c73f9c2a7722dfa165dca04' 
  AND token = 'OSpqWJVdbF4i6leySuvZt1Nx/C2rMQHm52mmBCUNwBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}