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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1bd43f9830f1efa49e556800127e47ea73a64bab859087e1778f757d73524c5' 
  AND token = 'fOLqHStpxfdCd6MeXu4Z9aaHdzw+jJ4EiFoVj3eC2Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}