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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8b0891abf81f751a223004fcc7f2b6ae4f9ab1c00211a4aeee441e259d0583' 
  AND token = '1AObYkNQ2K7mE9LYsGRZx/mGJC4bWfqcx0Y9XLoOdRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}