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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d9168a8fd3775bccd0e0e8f2c93c509d26eaba495aca99946a468a6cf78852' 
  AND token = 'PQVc8PWgAqFot9L8XhXwKDyATVpcTbC7gGP0qO3at/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}