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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ac64e0a8ebbaffb15dbe6773d3e9e10a27c4c5727f60a5d0d88199f0037c43' 
  AND token = '4BsELsg0wQ/ISmLk6k08bbdkI4kQZ0u+FPhiag3OiqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}