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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8594d70706361d54f0e3cb997aa77fd307644d7e33f61333c3836c049e405e67' 
  AND token = 'goS7mqDl0w6PYoax3e9GIw0ET27WengZnX27lOIs308=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}