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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ebf86d6391c92715ec30345e50d3b5ceb702c9760aa1b45fe07fbc04399f58' 
  AND token = 'bgS8sBt2IiqPM84JIKnxyny531PDjhjUWluuLhFuido=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}