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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72597fdfa33e4bebe65483222ddd4800541def66262f3dd8744d1ee6fa38fd88' 
  AND token = 'RJoTNybqZGs7lsfVobTc0hqqU0VpS0IOROBXStZWL2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}