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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4215c4b5da68804154c2cab24b5d4ee91b0cdf6bf85c36d62b61c015ae6a60' 
  AND token = 'nHVq7tBUzTSt642uZyvssKYoLyvEHr47IXvVgKrsYpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}