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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cec70e045ee4413f71855bcbee41905e1582d74f076142909cb2a719fc47cc8' 
  AND token = 'UAoT89OAXYpe/xdO6US4qIH+DxKPW15CvsfgxSVMzxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}