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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a1d7a35e70a0ce30051650d0e59d0ed841c0e06db45cb31114a8badc3144bd' 
  AND token = 'c4Vb/F0r4NeL4OvAb8AG5dK1PPGkyBimiWzuiHb2gdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}