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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29689fd21b9e1f95f4e6f66ea4012486a972c034504bbbb6a96bd7191228dc14' 
  AND token = 'dXG+G8YE49D/p/6zWQ0pEgr4r7oX4Yob2L3CcRhI5Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}