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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e570be56e7e3f356444cbd82fe59d42aee107e9ba3460b535a111678e0289489' 
  AND token = 'x9O0o2p+8K6gVx/PwtTFWB9nzZRKV3DsNPg9wTqMa3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}