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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f94d29a7f69d77a5dbc5132e02d2d375c3fd47a20edd1f32286eb038e8e9fb1' 
  AND token = 'EURSwasWxmR82xOmzg4scqXXP7C04TRYMfKOk3/p8co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}