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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12529c793b437463dc4bc004615b333e398ece4faf32229aa90ff4f6d16e5464' 
  AND token = '1M8KLzG3VKNk0vSiiVOKteYIto8SbC+F2Xxcy8AK4RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}