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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a5b6a69c7daa80c7aadf1c9d9cb88317541a3c36a697677381eea3b2ccdf8d' 
  AND token = 'Z+5B0Mi8QPeARDiw6Pcg84dTjz1HhbIaCgnHC09Sdwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}