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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9a95982d01b7d585becfb9632115216eb65953a2c593d610e504ca91365bb6' 
  AND token = '7WDZpbS43tvTf/iyOCQW0EqlMDSMDqg6h9Oz9b2SX3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}