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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e010adbf25f28c7a6e0fdc1f0878afed22a2625f2e584ef119a8e485c0bbf053' 
  AND token = 'LxVPc9TWMcReHw7UdybRIAXW7lsEvjKJuP7ZEU9h9kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}