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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d475e0e0f11bd1dca41522c443a57d8a7f0705563d0dec1d4f941347f8241f' 
  AND token = 'KOhY+QJ+wSwgXwYoDmhR86dAv5f2rQ6iqjYkvicS0/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}