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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3562a2a7920af4ff6ff12042070d3cbf60deca6b5c640df24f07155e5a5397c3' 
  AND token = 'A54FKKSj2Ny0Nh+r3d3xgiE6SYsdLuEADdbe57NsmuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}