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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6453ccc9ea5aa0bc6fae97a958c0b5c1910cf5ca91940f31d28d9476240db7cb' 
  AND token = 'EWjsCSGlQM1+CnRNZU4n1ljVn0lG3zYmYrfpKD493aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}