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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0e35b87f4026c91c5bca086df30d4d9e7dee86b090647e77c1c5909d595fbe' 
  AND token = 'ZVbgdDdWkRgBoIl83/Z//FjyCkx/PjKf0siVDHrrZ0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}