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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c549ec9127a746585f6740729ad74fbb7ee2dd030ef084accf92c28c3dab4e' 
  AND token = 'ncdERr5YQ4De4DDJPDTsLUuyqiO5VyVqWoNtfVheGW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}