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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d81ebf058f7718f736968d689b983d87de3cc0a97bdd63a5c942a3e85d1902d' 
  AND token = 'Kqx1bktA/j7T7Xid9YkPB4i/GRy+SH8yUm25AAkdGf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}