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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e1df7caca6c0d0043b0c56706bf266c11bb65e2b3d0b66235afbff65413bf0' 
  AND token = 'Pu2RCrRc24Ai4TsbVertmiVVWDKc6VLT6IQO2LdvBdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}