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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604b4bc5c5311e8f790e631ac5ceda290f841af20d2f647b25e32207ba0df2b7' 
  AND token = 'bqwl2prvuF0sOpbh7P+80Vjzu+0vL4x/iVbZUEy6jTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}