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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fc09595ffbc16613b31baac376f5dd594a500173d8498ea1ffd0e3f4e32f6c' 
  AND token = '16QuUEjfbcMIIecxfqdsrUmKg5G80rrCa5xoeCT8Wjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}