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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe51fcacda5274af591a5f7ed1558e1a6eefe2bcb5075519b2c10019da1880c' 
  AND token = '/p/89DchVw+6BCUAtw4n3hP6jrSa1361zyNHKaeSCLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}