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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd749c968d0d02fdfdb47197a73a9ac70c338d59fd5b284f3a7372e53c73ca780' 
  AND token = 'WJ5LgCl7WqFIqClp2cHcu3yaMS0e8eEgpw1iUjhHecU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}