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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52cc40174c7d1daca26c763eb77647e9c2a761b07db0cb7493bb9fac33331b4c' 
  AND token = 'FMIsar+vFCK/FE9KA2Gzs5NL9SJ98SsCByEmAocfCgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}