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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc0e81a5574a4f72fc124f7e379b67007c05c6aadf6d5f05f9a4e8ac4887261' 
  AND token = '786LFBFVhN+SDfbd/t8tWTLjLCtmF1ywMgqi+XxIfow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}