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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab46bd202f7c71f77420558ccfaf24a9c43805668e0899d244cbcbac1bf3f715' 
  AND token = '16cJGh5/R2wlBwutdp5HpD7sMKBMn6pIFSAzN1IPNH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}