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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5e561ca41d74d1fbd3f7f62fd6e0a16e46c89554e130dd27da1b465ab1c213' 
  AND token = '1+ScsRUWbR1PrF74tHzWjtFG2WXWRvAkGgH0ZKJyi7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}