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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57f0578c13dc361254a70e9de4174e3def55818d47d63d3ce1bde5435a9e7f2' 
  AND token = 'GN3/88fvZaR7C/r7e3RvfRxJuEcRmKK1CZGbSYDJgB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}