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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754c7dd540dce934947324a84402100c1f3ca5f8779fe65203219d1c90084719' 
  AND token = 'E8yb2zrcbO2+X9B/Ah/wNS4nM4ky712Ue5UykmoK5Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}