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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b776520171ed6faec7941409d28965e78d21db4d32e5339fef8f5da1c02f0006' 
  AND token = 'IPHSj1oUU7ugYbqUfEPZcBSB/KIG78lnMhKB4ZZ0ye0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}