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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7e6436c5bf38aabf73dfe315abee32e266a64d9abecd7e04f4739f2d37668d' 
  AND token = '+0d/PRXSe0YHYJ9STa19bLaOJniFcTFWlUk2zeOWALg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}