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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01afe449c183bbf0150b8b15258adb40ac955186d819971b5edaf38fdccfa901' 
  AND token = 'N4e2gOaWCccKQJw/pqOM8jIGIA1T8PsB/LABAJHV92s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}