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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a63e8c272285a1a8544e8f990d30144bad6c7b4c75137f659375365288f7e6b' 
  AND token = 'I1P9E2OeDEPjE+FoNwH8ReOPn1Y3HAnEaZcFtCY35eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}