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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad2006c7988f762e78c2cc6a07d4226dadffd812008c28c4eaa8d462089e913' 
  AND token = '0R7MWx9LoHLC46IA8ebT9lU874m+h4kgnXniY7YNF3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}