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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5481625018a1b64320c9cc17005e51a9b9dd8075d8578ed08d56ce7be3b4a4d9' 
  AND token = '87tZ3FGvdabRONGCgQwY/GDs+GMva+f3rdBCIxbG3iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}