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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e8d644d7436cc3f5177f99509520df329c211195b0b868cfa4da4e0581cea4' 
  AND token = 'FO2m0erUjtCOVN3kU5fIrBTWAh7ujrl/dpDTL8afZuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}