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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3720f6f3b5ed5b5890904d2cb09ce0f0cabd3ad2b0bac0578778aa49538405a' 
  AND token = 'I7lElDMJ5A7dfhoN8JuOE1dikS/bnaE+qKvBjtGsWE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}