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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8912554ab56b4f08ee55ef8479ed280768cc312cd5f3000862100d882a852259' 
  AND token = 'TRjDtOt8xiPA7rpu/OfhW0Fk9mmAvTjq9zZ90GWBKPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}