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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c81973c4394126ed8cb986fac533f9f7fc32e0bab01ffa35aeb312b3a5165b5' 
  AND token = 'zXxeh9f+EeESAKFEmLEeL4AEoIRIH9bxy4vDD0G5Zag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}