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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7112a52aa2cf7fd0d76e60075a9366ea73e78610da5ca7be2ceb000d59a7c47' 
  AND token = '90rmXTKX12BcrGv+TPSYUDx6UNsy8s9P17ryXnbbx1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}