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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81fd97865445301a0fdd1af31f326c4e696743e7ca6c2e6a56a48bb339dc0c6' 
  AND token = '6HDweI9W1bNiwKVKW7Zw4ck4mDi9QZy0tJDpgPDNyZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}