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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25a93401a54a32b8cd2c254069ff9fa71ab252031f8259fbbd718fc98ecdac7' 
  AND token = 'IpeLeQ+OOIGbbCId0PbviBGpZE19rydfk9aWLrWM6as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}